RT-PCR Results and Chest CT Imaging Features in Patients Hospitalized to Yozgat City Hospital with COVID-19 Suspicion

INTRODUCTION: This study aims to investigate Chest CT findings and RT-PCR results in patients hospitalized with suspicion of COVID-19.
METHODS: Between 15 March and 15 May 2020, patients hospitalized in Yozgat City Hospital with suspicion of Covid-19 were evaluated retrospectively. Chest CT findings were classified according to the modified COVID-19 reporting system created for this study. RT-PCR reference diagnostic test was accepted and the diagnostic performance of CT was evaluated.
RESULTS: A total of 498 patients [54±22 (0; 96)] were included in the study. The number of male patients [323 (65%)] was higher than female [175 (35%)]. RT-PCR test was positive in 94 (19%) of the patients. Patients with positive test results were found to be younger than negative ones. Chest CT was positive in 173 (35%) patients: 13% COVID-19 typical findings, 7% high suspect findings, 15% low suspect findings. The sensitivity of CT was 49%, the specificity was 69%, and the sensitivity of RT-PCR was 69%. Infiltrations in CT positive cases were seen in the following areas: 52% in both lungs, 40% in all lobes, 34% in lower lobes, 47% in the posterior, 43% in the anterior and posterior lung regions, 60% in the peripheral, 30% peripheral and central lung regions.
DISCUSSION AND CONCLUSION: The sensitivity of chest CT in the diagnosis of COVID-19 was relatively low, but had high specificity. It may be more beneficial to use CT for rapid diagnosis in regions with a high prevalence of COVID-19. Using a standardized report format to evaluate CT findings seems necessary for patient management.

COVID-19 Þüphesiyle Yozgat Þehir Hastanesine Yatan Olgularda RT-PCR Sonuçlarý ve Toraks BT Görüntüleme Özellikleri

GÝRÝÞ ve AMAÇ: Bu çalýþmanýn amacý COVID-19 þüphesiyle hastaneye yatýrýlan olgularýn Toraks BT bulgularýný ve RT-PCR sonuçlarýný incelemektir.
YÖNTEM ve GEREÇLER: 15 Mart-15 Mayýs 2020 tarihleri arasýnda, Yozgat Þehir Hastanesine COVID-19 þüphesiyle yatýrýlan olgular geriye dönük olarak deðerlendirilmiþtir. Toraks BT bulgularý bu çalýþma için oluþturulan modifiye COVID-19 raporlama sistemine göre sýnýflandýrýlmýþtýr. RT-PCR referans taný testi kabul edilerek BT’nin tanýsal performansý deðerlendirilmiþtir.
BULGULAR: Toplam 498 olgu [54±22 (0; 96)] çalýþmaya dahil edildi. Erkek olgu sayýsý [323 (%65)] kadýnlardan [175 (%35)] daha fazlaydý. Olgularýn 94’ünde (%19) RT-PCR testi pozitif sonuçlanmýþtý. Test sonucu pozitif olan hastalarýn negatif olanlara göre daha küçük yaþta olduðu bulundu. 173 (%35) olguda toraks BT pozitif saptandý: %13 COVID-19 uyumlu bulgular, %7 yüksek þüpheli bulgular, %15 düþük þüpheli bulgular. BT’nin duyarlýlýðý %49, özgüllüðü %69, RT-PCR’ýn duyarlýlýðý ise %69 olarak bulundu. BT pozitif olgulardaki infiltrasyonlarýn %52’si her iki akciðerde, %40’ý tüm loblarda, %34 alt loblarda, %47’si arka, %43’ü ön ve arka akciðer alanlarýnda, %60’ý periferik, %30’u periferik ve santral akciðer alanlarýnda görüldü.
TARTIÞMA ve SONUÇ: Toraks BT’nin COVID-19 tanýsýndaki duyarlýlýðý göreceli düþük ancak özgüllüðü yüksek bulunmuþtur. BT’nin hýzlý taný için COVID-19 prevalansýnýn yüksek olduðu bölgelerde kullanýlmasý daha faydalý olabilir. BT bulgularýný yorumlamada standardize edilmiþ bir rapor formatýný kullanmak hasta yönetimi için gerekli görünmektedir.